Extrahepatic autoimmune manifestations of chronic hepatitis C virus infection

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Extrahepatic autoimmune manifestations of chronic hepatitis C virus infection.

The hepatitis C virus infection (HCV) is currently a worldwide health problem. The chronic infection may progress to cirrhosis with the subsequent development of complications including ascities, encephalopathy, upper gastrointestinal tract bleeding and hepatocellular carcinoma. The HCV is a linear, single-stranded RNA virus of the Flaviviridae family that was identified in 1989 by Choo et al. ...

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Extrahepatic manifestations of chronic hepatitis C virus infection

During hepatitis virus (HCV) chronic infection, extrahepatic manifestations are frequent and polymorphous. Initial description reported in large cohort of patients HCV-related autoimmune and/or lymphoproliferative disorders, from mixed cryoglobulinemia vasculitis to frank lymphomas. The relationship between HCV infection and such immune-related diseases has been formally demonstrated by epidemi...

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Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection.

Chronic hepatitis C virus (HCV) infection has been associated with both organ-specific and systemic autoimmune diseases, with cryoglobulinemia being the most frequent associated disease. Experimental, virologic, and clinical evidence have demon-strated a close association between HCV infection and some systemic autoimmune diseases, especially Sjögren's syndrome, but also rheumatoid arthritis an...

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Extrahepatic manifestations in hepatitis C virus infection

Hepatitis C virus predominantly affects the liver, although it may also produce a number of extrahepatic manifestations, such as mixed cryoglobulinemia, salivary and lacrimal gland dysfunction, and several types of kidney disease. The pathogenesis of these conditions is not completely understood, but immunologic mechanisms are involved in many cases. In some patients with hepatitis C virus infe...

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Morphologic Features of Extrahepatic Manifestations of Hepatitis C Virus Infection

Cirrhosis and hepatocellular carcinoma are the prototypic complications of chronic hepatitis C virus infection in the liver. However, hepatitis C virus also affects a variety of other organs that may lead to significant morbidity and mortality. Extrahepatic manifestations of hepatitis C infection include a multitude of disease processes affecting the small vessels, skin, kidneys, salivary gland...

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ژورنال

عنوان ژورنال: Annals of Hepatology

سال: 2006

ISSN: 1665-2681

DOI: 10.1016/s1665-2681(19)32000-9